Principal Investigator: Charles A. Warren, Ph.D., University of Illinois at Chicago
Awarded $172,492 in 1999

Aim: Investigate whether certain event-related brain potential (ERP) abnormalities in response to gambling feedback might reflect a reward deficiency syndrome, whose severity theoretically is driven partly by presence of the dopamine D2 receptor gene, A1 variant (D2A1).

Principal Investigator: Hans Breiter, MD, Massachusetts General Hospital
Awarded $172,500 in 1999

Aim: Understand brain activation produced by a monetary reward in a gambling-like experiment. As a result of this grant support, the lead investigator received support from National Institutes of Health and the Office of National Drug Control Policy.

Aharon, I., Etcoff, N., Ariely, D., Chabris, C. F., O’Connor, E., & Breiter, H. C. (2001). Beautiful faces have variable reward value: fMRI and behavioral evidence. Neuron, 32(3), 537-551.

Breiter, H. C., Aharon, I., Kahneman, D., Dale, A. & Shizgal, P. (2001). Functional imaging of neural responses to expectancy and experience of monetary gains and losses. Neuron, 30, 619-639.

Breiter, H., & Gasic, G. P. (2004). A general circuitry processing reward/aversion information and its implications for neuropsychiatric illness. In M. Gazzaniga (Ed.), The Cognitive Neurosciences, III (3rd ed., pp. 1043-1065). Cambridge: MIT Press.

Makris, N., Gasic, G.P., Seidman, L.J., Goldstein, J.M., Gastfriend, D.R., Elman, I., Albaugh, M.D., Hodge, S.M., Ziegler, D.A., Sheahan, F.S., Caviness, V.S., Tsuang, M.T., Kennedy, D.N., Hyman, S.E., Rosen, B.R., Breiter, H.C. (2004). Decreased absolute amygdala volume in cocaine addicts. Neuron, 4(4), 729-40.

Principal Investigator: Renee Cunningham-Williams, Ph.D., Washington University, St. Louis
Awarded $112,021 in 1999

Aim: Develop and test a new assessment instrument for gambling disorder. The grant provided seed money that helped the lead investigator secure funding from the National Institute on Drug Abuse and National Institute of Mental Health.

Cunningham-Williams, R.M., & Cottler, L. B. (2001). The epidemiology of pathological gambling. Seminars in Clinical Neuropsychiatry, 6, 155-166.

Cunningham-Williams, R.M., Cottler, L.B., & Womack, S.B. (2004). Epidemiology. In J.E. Grant and M.N. Potenza, Pathological gambling: A clinical guide to treatment, American Psychiatric Press, 25-36.

Cunningham-Williams, R.M., Grucza, R., Cottler, L.B., Womack, S.B., Books, S.J., Przybeck, T., Spitznagel, E.L., & Cloninger, R. (2005). Prevalence of pathological gambling among St. Louis area household residents. Journal of Psychiatric Research, 39, 377-90.

Principal Investigator: Lawrence E. Jones, Ph.D., University of Illinois at Urbana-Champaign
Awarded $172,155 in 1999

Aim: Identify and describe several distinct “types” of gambling styles and strategies, including ones that will distinguish between subtypes of pathological gamblers.

Principal Investigator: Nigel E. Turner, Ph.D., Centre for Addiction and Mental Health, Toronto
Awarded $88,296 in 1999

Aim: Develop and test an interactive prevention package designed to enhance the students’ understanding of the role of randomness, probability and emotion in non-problem gambling. The findings were published in the Journal of Gambling Studies.

Turner, N. E., Macdonald, J., & Somerset, M. (2008). Life skills, mathematical reasoning and critical thinking: A curriculum for the prevention of problem gambling. Journal of Gambling Studies, 24(3), 367-80.

Principal Investigator: Jennifer Langhinrichsen-Rohling, Ph.D., University of South Alabama
Awarded $125,800 in 1999

Aim: Understand the role of demographic, individual, family, and peer variables in the development of gambling problems among adolescents.

Langhinrichsen-Rohling, J. (2004). The associations among gambling, depression, and suicidal behavior in adolescents. In J. Derevensky and R. Gupta (Eds.), Gambling Problems in Youth: Theoretical and Applied Perspectives. New York: Kluwer Academic/Plenum Publishers.

Langhinrichsen-Rohling, J., Rohde, P., Seeley, J. R., & Rohling, M. L. (2004). Individual, family, and peer correlates of adolescent gambling. Journal of Gambling Studies, 20, 23-46.

Langhinrichsen-Rohling, J., Rohling, M. L., Rohde, P., & Seeley, J. R. (2004). The SOGS-RA versus the MAGS-7: Prevalence estimates and classification congruence. Journal of Gambling Studies, 20, 259-281.