Large Grant: “Evaluating the Potential of Mixed-Function Serotonergic Compounds for Treatment of Gambling Disorders”

Principal Investigator: T. Celeste Napier, PhD, Rush University Medical Center
Awarded $172,500 in 2012

Aim: Expedite the discovery and development of effective treatment strategies for gambling disorder by using a unique rat models to determine if medications used for other diseases can be repurposed for the treatment of gambling disorders.

Rokosik, S. L., & Napier, T. C. (2012). Pramipexole-induced increased probabilistic discounting: comparison between a rodent model of Parkinson’s disease and controls. Neuropsychopharmacology, 37(6), 1397-1408.

Tedford, S.E., Holtz, N.A., Persons, A.L., & Napier, T.C. (2014). A new approach to assess gambling-like behavior in laboratory rats: using intracranial self-stimulation as a positive reinforcer. Frontiers in Behavioral Neuroscience, 8.

Year: 2012
Type: Project Grants