Archive for category: Project Grants

Principal Investigator: Howard J. Shaffer, Ph.D., Harvard Medical School and Cambridge Health Alliance
Awarded $1.14 million a year from 2001 – 2009

The NCRG delegated the research and education functions of the NCRG to the Division on Addiction, Harvard Medical School (HMS) and Cambridge Health Alliance, a teaching hospital of HMS, from 2001 to 2009. This grant supported the intramural research conducted by the Division on Addiction faculty and also the extramural research grants program that sponsored the research projects listed in this section from 2001 through 2008.

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Boudreau, A., LaBrie, R. A., and Shaffer, H.J. (2009). Towards DSM-V: “Shadow Syndrome” symptom patterns among pathological gamblers. Addiction Research & Theory, 17(4), 406-419.

Gebauer, L., LaBrie, R. A., and Shaffer, H. J. (2010). Optimizing DSM-IV classification accuracy: A brief biosocial screen for detecting current gambling disorders among gamblers in the general household population. Canadian Journal of Psychiatry, 55(2), 82-90.

Kleschinsky, J. H., Bosworth, L. B., Nelson, S.E., Walsh, E. K., & Shaffer, H.J. (2009). Persistence pays off: Follow-up methods for difficult-to-track longitudinal samples. Journal of Studies on Alcohol and Drugs, 70(5), 751-761.

Kleschinsky, J. H., Kaplan, S. A., Nelson, S. E., LaBrie, R. A., & Shaffer, H. J. (2008). The Missouri Voluntary Exclusion Program: Participant Experiences across 10 Years. Boston, MA: Division on Addictions, Harvard Medical School.

LaBrie, R. A., Peller, A. J., LaPlante, D. A., Bernhard, B., Harper, A., Schrier, T., & Shaffer, H. J. (2012). A brief self-help toolkit intervention for gambling problems: A randomized multi-site trial. American Journal of Orthopsychiatry, 82(2), 278-289. doi: 10.1111/j.1939-0025.2012.01157.x

LaBrie, R.A., Nelson, S.E., LaPlante, D.A., Peller, A.J., Caro, G., & Shaffer, H.J. (2007). Missouri casino self-excluders:  Distributions across time and space. Journal of Gambling Studies, 23 (2), 231-243.

LaBrie, R.A., & Shaffer, H.J. (2007). Editorial: Gambling with Adolescent Health. Journal of Adolescent Health, 40(5), 387-389.

LaBrie, R. A., Shaffer, H. J., LaPlante, D., & Wechsler, H. (2003). Correlates of college student gambling in the United States. Journal of American College Health, 52, 53-62.

LaPlante, D. A., Gray, H. M., Bosworth, L., & Shaffer, H. J. (2010). Thirty years of lottery public health research: methodological strategies and trends. Journal of Gambling Studies, 26(2), 301-329.

LaPlante, D. A., Nelson, S. E., LaBrie, R. A., & Shaffer, H. J. (2006). Men and women playing games: Gender and the gambling preferences of Iowa Gambling Treatment Program participants. Journal of Gambling Studies, 22(1), 65-80.

LaPlante, D.A., Nelson, S.E., LaBrie, R.A., & Shaffer, H.J. (2008). Stability and progression of disordered gambling: lessons from longitudinal studies. Canadian Journal of Psychiatry, 53(1), 52-60.

LaPlante, D.A., & Shaffer, H. J. (2007). Understanding the influence of gambling opportunities: Expanding exposure models to include adaptation. American Journal of Orthopsychiatry, 77(4), 616-623.

Lee, T. K., LaBrie, R.A., Seung Rhee, H., Shaffer, H. J. (2008). A study of South Korean casino employees and gambling problems. Occupational Medicine, 58(3), 191-197.

Lee T. K., LaBrie, R. A., Grant, J. E., Kim, S. W., & Shaffer, H. J. (2007). The structure of pathological gambling among Korean gamblers: A cluster and factor analysis of clinical and demographic characteristics. International Journal of Mental Health and Addiction, 6, 551-563.

Nelson, S. E., Gebauer, L., LaBrie, R. A., & Shaffer, H. J. (2009). Gambling problem symptom patterns and stability across individual and timeframe. Psychology of Addictive Behaviors, 23(3), 523-533.

Nelson, S. E., Kleschinsky, J. H., LaBrie, R. A., Kaplan, S., & Shaffer, H. J. (2010). One decade of self-exclusion: Missouri casino self-excluders four to ten years after enrollment. Journal of Gambling Studies, 26(1), 129-144.

Nelson, T.F., LaBrie, R.A., LaPlante, D.A., Stanton, M., Shaffer, H.J., & Wechsler, H. (2007). Sports betting and other gambling in athletes, fans, and other college students. Research Quarterly on Exercise and Sport, 78(4), 271-83.

Nelson, S. E., LaPlante, D. A., LaBrie, R. A., & Shaffer, H. J. (2006). The proxy effect: Gender and gambling problem trajectories of Iowa Gambling Treatment Program participants. Journal of Gambling Studies, 22(2), 221-240.

Odegaard, S. S., Peller, A., & Shaffer, H. J. (2005). Addiction as syndrome. Paradigm, 9, 12-13, 22.

Peller, A. J., LaPlante, D. A., & Shaffer, H. J. (2008). Parameters for safer gambling behavior: Examining the empirical research. Journal of Gambling Studies, 24(4), 519-534. doi: 10.1007/s10899-008-9097-5

Shaffer, H. J. (2003). A critical view of pathological gambling and addiction: Comorbidity makes for syndromes and other strange bedfellows. In G. Reith (Ed.), For fun or profit? The controversies of the expansion of commercial gambling. New York: Prometheus Books.

Shaffer, H. J. (2004). Foreword. In J. L. Derevensky & R. Gupta (Eds.), Gambling problems in youth: Theoretical and applied perspectives (pp. v-x). New York: Kluwer Academic/Plenum Publishers.

Shaffer, H.J. (2005). From disabling to enabling the public interest: Natural transitions from gambling exposure to adaptation and self-regulation. Addiction, 100(9), 1227-35; discussion 1235.

Shaffer, H. J. (2007). Considering the unimaginable: Challenges to accepting self-change or natural recovery from addiction (Foreword). In H. Klingemann & L. Carter-Sobell (Eds.), Promoting Self-Change from Addictive Behaviors: Practical Implications for Policy, Prevention, and Treatment (second edition). New York: Springer.

Shaffer, H. J., & Albanese, M. (2004). Addiction’s defining characteristics. In R. H. Coombs (Ed.), Addiction Counseling Review: Preparing for Comprehensive, Certification and Licensing Exams: Lahaska Press.

Shaffer, H. J., Dickerson, M., Derevensky, J., Winters, K., George, E., Karlins, M., & Bethune, W. (2001). Considering the ethics of public claims: An appeal for scientific maturity. Journal of Gambling Studies, 17, 1-4.

Shaffer, H.J., Donato, A.N., LaBrie, R.A., Kidman, R.C., & LaPlante, D.A. (2005). The epidemiology of college alcohol and gambling policies. Harm Reduction Journal, 2(1), 1.

Shaffer, H. J. & Freed, C. R. (2005). The assessment of gambling related disorders. In D. Donovan & G. A. Marlatt (Eds.), Assessment of Addictive Behaviors. New York: Guilford.

Shaffer, H. J., Freed, C.R., & Healea, D. (2002). Gambling disorders among homeless persons with substance use disorders seeking treatment at a community center. Psychiatric Services, 55(9), 1112-1117.

Shaffer, H. J. & Kidman, R. (2003). Shifting perspectives on gambling and addiction. Journal of Gambling Studies, 19, 1-6.

Shaffer, H. J. & Kidman, R. (2004). Gambling and the public health. In J. E. Grant & M. N. Potenza (Eds.), Pathological gambling: A clinical guide to treatment. Washington, DC: American Psychiatric Publishing, Inc.

Shaffer, H.J., LaBrie, R., & LaPlante D. (2004). Laying the foundation for quantifying regional exposure to social phenomena: Considering the case of legalized gambling as a public health toxin. Psychology of Addictive Behaviors, 18, 40-48.

Shaffer, H. J., LaBrie, R. A., LaPlante, D., Kidman, R., & Donato, A. (2005). The Iowa Gambling Treatment Program: Treatment outcomes for a follow-up sample. Journal of Gambling Studies, 21, 59-71.

Shaffer, H. J., LaBrie, R., LaPlante, D., Kidman, R. & Korn, D. A. (2002). Evaluating the Iowa Department of Public Health Gambling Treatment Program: Four years of evidence. Boston: Harvard Medical School, Division on Addictions.

Shaffer, H. J., LaBrie, R. A., LaPlante, D. A., Kidman, R. C., & Nelson, S. E. (2004). The Iowa Department of Public Health Gambling Treatment Services: Follow-up Study Report (Technical Report #20304-200). Boston: Harvard Medical School.

Shaffer, H. J., LaBrie, R. A., LaPlante, D. A., & Nelson, S. B. (2004). Disordered gambling in Missouri: Regional differences in the need for treatment. Phase I Report prepared for: The Greater Kansas City Community Foundation in partial fulfillment of the research grant “Evaluation Services with Regard to the Regional Impact of Compulsive Gambling” supported by the Port Authority Problem Gambling Fund.

Shaffer, H.J., LaBrie, R., LaPlante D., Nelson, S. E. & Stanton, M. (2004). The road less travelled: Moving from distribution to determinants in the study of gambling epidemiology. Canadian Journal of Psychiatry,48(8),159-171.

Shaffer, H. J. & LaPlante, D. (2005). The treatment of gambling related disorders. In G. A. Marlatt & D. M. Donovan (Eds.), Relapse Prevention (second ed.). New York: Guilford.

Shaffer, H., LaPlante, D., LaBrie, R., Kidman, R., Donato, A., & Stanton, M. (2004) Toward a syndrome model of addiction: Multiple expressions, common etiology. Harvard Review of Psychiatry, 12, 367-374.

Shaffer, H. J., Nelson, S. E., LaPlante, D. A., LaBrie, R. A., Albanese, M., & Caro, G. (2007). The epidemiology of psychiatric disorders among repeat DUI offenders accepting a treatment-sentencing option. Journal of Consulting and Clinical Psychology, 75(5), 795–804.

Shaffer, H. J., Peller, A. J., LaPlante, D. A., Nelson, S. E., & LaBrie, R. A. (2010). Toward a paradigm shift in Internet gambling research: From opinion and self-report to actual behavior. Addiction Research & Theory, 18(3), 270–283.

Shaffer, H.J., Stanton, M.V., Nelson, S.E. (2006). Trends in gambling studies research: quantifying, categorizing and describing citations. Journal of Gambling Studies, 22(4), 427-42.

Xuan, Z., & Shaffer, H. (2009). How do gamblers end gambling: Longitudinal analysis of Internet gambling behaviors prior to account closure due to gambling related problems. Journal of Gambling Studies, 25(2), 239–252.

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Principal Investigator: Kenneth Kendler, Ph.D., Virginia Commonwealth University
Awarded $172,500 in 2001

Aim: Assess gambling problems in a registry of 7,500 adult male and female twins in order to elucidate the heritability of pathological gambling, clarifying its relationship with milder forms of problem gambling, and determining the genetic and environmental relationship between pathological gambling and major psychiatric disorders and personality traits.

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Blanco, C., Myers, J., & Kendler, K. S. (2012). Gambling, disordered gambling and their association with major depression and substance use: a web-based cohort and twin-sibling study. Psychological Medicine, 42(3), 497–508. https://doi.org/10.1017/S0033291711001401

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Principal Investigator: Rani Desai, Ph.D., Yale School of Medicine
Awarded $172,477 in 2001

Aim:  Assess the prevalence and types of gambling and related behaviors and problems in patients with schizophrenia and the influence of a co-occurring diagnosis with a substance use disorder on gambling behaviors.

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Desai, R. A., & Potenza, M. N. (2009). A cross-sectional study of problem and pathological gambling in patients with schizophrenia/schizoaffective disorder. Journal of Clinical Psychiatry, 70(9), 1250-1267. https://doi.org/10.4088/JCP.08m04359

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Principal Investigator: Jody Tanabe, MD, University of Colorado Health Sciences Center
Awarded $172,500 in 2003

Aim: Test hypothesis that defects in ventral medial frontal processing lead to impaired decisions that involve risk.

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Tanabe, J., Thompson, L., Claus, E., Dalwani, M., Hutchison, K., & Banich, M. T. (2007). Prefrontal cortex activity is reduced in gambling and nongambling substance users during decision-making. Human Brain Mapping, 28(12), 1276–86. https://doi.org/10.1002/hbm.20344

Tanabe, J., Tregellas, J. R., Thompson, L., Dalwani, M., Owens, E., Crowley, T., & Banich, M. (2009). Medial orbitofrontal cortex gray matter is reduced in abstinent substance dependent individuals. Biological Psychiatry, 65(2), 160–164. https://doi.org/10.1016/j.biopsych.2008.07.030

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Principal Investigator: Silvia Martins, MD, Ph.D., Johns Hopkins Bloomberg School of Public Health
Awarded $23,000 in 2004

Aim: Understand the gambling habits, gambling problems and comorbid psychiatric problems in a sample of 15-16 year old youth (90% African American) from Baltimore city. This grant enabled the PI to secure funding from the National Institute of Child Health and Development to continue the study.

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Martins, S. S., Storr, C. L., Ialongo, N. S., & Chilcoat, H. D. (2008). Gender differences in mental health characteristics and gambling among African-American adolescent gamblers. American Journal on Addictions, 17(2), 126–34. https://doi.org/791991387 [pii] 10.1080/10550490701861227

Martins, S. S., Storr, C. L., Ialongo, N. S., & Chilcoat, H. D. (2007). Mental health and gambling in urban female adolescents. Journal of Adolescent Health, 40(5), 463–5. https://doi.org/S1054-139X(06)00598-2 [pii] 10.1016/j.jadohealth.2006.12.008

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